Chronic myelomonocytic leukemia can present with diffuse planar xanthoma

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Chronic myelomonocytic leukemia can present with diffuse planar xanthoma.

There is a documented association between diffuse planar xanthoma and chronic myelomonocytic leukemia. Previous accounts have hypothesized that patients with multiple lesions or extensive cutaneous disease are more likely to have an underlying abnormality of the reticuloendothelial system. However, we document a 62-year-old woman with a large pruritic yellow-orange plaque on the chest and lower...

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Auer Rods in Chronic Myelomonocytic Leukemia Can Change the Diagnosis

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping morphological features of myelodysplastic and myeloproliferative disease and a potential risk of transformation to acute myeloid leukemia. Presence of Auer rods in CMML is a rare finding and the presence of an occasional Auer rod gives the diagnosis of CMML-2 in spite of the presence of <5% blas...

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A Rare Case of Acute Myeloid Leukemia with Translocation (3:3) Presenting with Features of Chronic Myelomonocytic Leukemia

Background: Acute Myeloid Leukemia (AML) with translocation (3,3) is a form of AML that may present de novo or may arise from a previous myelodysplastic syndrome. It is often associated with normal or elevated peripheral blood platelet count and increased bone marrow megakaryocytes with associated multi lineage dysplasia. A subset of patients present with hepatosplenomegaly while a few cases h...

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Prognosis of chronic myelomonocytic leukemia.

BACKGROUND Cytopenia caused by ineffective hematopoiesis and monocyte overproduction coexist in CMML, providing grounds for discussion to supporters of a dysplastic versus a proliferative identity for CMML. Follow-up information from a large series of patients may contribute to clarifying the position of this infrequent disease. METHODS We analyzed data from 77 patients followed in five insti...

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Diffuse normolipemic plane Xanthoma in adult T-cell lymphoma/leukemia: A case report

Diffuse normolipemic plane xanthoma is a rare disorder often seen as a para-neoplastic manifestation accompanied with gammopathies and hematologic disorders. In this report, a 44-year-old man is presented who was referred to us due to developing erythematous papules on the hands and yellow patches on different parts of the body. Based on cell blood count, peripheral blood smear and positive ant...

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ژورنال

عنوان ژورنال: Dermatology Online Journal

سال: 2014

ISSN: 1087-2108

DOI: 10.5070/d3207023143